The discovery of the Dural Pulse by Dr. John E. Upledger was the foundation for the groundbreaking work that he would later coin as CranioSacral Therapy. The development of this therapeutic approach earned Dr. Upledger recognition in TIME magazine as one of America's "Next Wave of Innovators" for his proven clinical applications of this therapy.

From 1975 to 1983, Dr. Upledger was a professor of biomechanics at the College of Osteopathic Medicine at Michigan State University. While he was there he led a team of anatomists, physiologists, biophysicists and bioengineers who performed and published the clinical research that formed the basis for CranioSacral Therapy.

In 1985, after decades of research, Dr. Upledger founded Upledger Institute International to teach people worldwide about the value of this effective approach. Today, the Institute is one of the most respected training venues in the world, with more than 100,000 alumni. Dr. Upledger also founded the Upledger Clinic the same year to provide treatment to individuals suffering from pain and dysfunction, and to continue his groundbreaking research in a clinical setting.